I can’t see the “first comment” or verify the specific study from your message alone, but I can help you interpret what this kind of claim usually means.
Statements like this are often referring to large observational studies on statins (cholesterol-lowering medications). Here’s the key context:
What large studies on statin “side effects” often find
- Many people who stop statins due to symptoms (like muscle pain) don’t actually experience those symptoms caused by the drug itself
- In blinded trials, muscle-related complaints are often similar in placebo and statin groups
- A lot of reported side effects may be influenced by a nocebo effect (expecting harm → noticing normal aches more strongly)
What “150,000 patients” studies usually show
- Statins significantly reduce risk of heart attack and stroke in high-risk people
- Serious side effects are rare
- Most patients who restart statins tolerate them well or can switch to a different type/dose
Important nuance
This doesn’t mean side effects are imaginary. Some people do experience real issues (especially at higher doses or with certain drug interactions), but:
- The overall rate of true intolerance is lower than many people think
- Many cases can be managed by adjusting dose or switching statins
If you want, paste the “first comment” or the study claim you saw, and I can break down whether it’s accurate or exaggerated.
